|previous article in this issue||next article in this issue|
Document Details :
Title: Een 73-jarige man met smaakstoornissen en ernstige vermagering
Author(s): MOUBAX K, GEORGE C
Journal: Tijdschrift voor Geneeskunde
Volume: 69 Issue: 13 Date: 2013
A 73-year-old man with loss of taste and serious weight loss
The medical history of a 73-year-old man with complaints of taste loss and serious weight loss since several months is reported. Extended investigations by the neurologist and the ear-nose-throat specialist revealed no real explanation. Ultimately, the patient developed liver failure with severe cholestasis. A liver biopsy revealed amyloid accumulation at the space of Disse.
Systemic amyloidosis is a severe disease. An overview of the involvement of the liver and the gastro-intestinal tractus, as well as the diagnosis and treatment options are described.