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Document Details :
Title: Prognostic value of CHA2DS2-VASc score in patients with ST-segment elevation myocardial infarction who underwent primary percutaneous coronary intervention
Author(s): M.H. Satilmisoglu , M. Gul , G. Yildiz , O. Akgul , M. Kaya , H.A. Cakmak , E. Akkaya , S. Aslan , M.T. Ameri , S.O. Ozyilmaz , A. Yildirim
Journal: Acta Cardiologica
Volume: 71 Issue: 6 Date: 2016
Objectives: The aim of the study was to investigate the relationship between CHA2DS2-VASc score and in-hospital and long-term all-cause and cardiovascular mortality in patients with STEMI who underwent primary PCI.
Methods: In this retrospective study, 604 patients, admitted to the emergency department with a diagnosis of STEMI, were included. The study patients were divided into three risk groups according to CHA2DS2-VASc score: low-risk group (1 point), moderate-risk group (2 points), and high-risk group (3 points and higher), respectively.
Results: The mean follow-up time was 680 ± 286 days. In the high-risk group, the rates of in-hospital and long-term all-cause and cardiovascular mortality were higher than in the other groups. The Kaplan-Meier curves for the group with CHA2DS2-VASc scores > 2 indicated a significantly shorter long-term survival (P < 0.001). In the receiver operating characteristic curve analysis, CHA2DS2-VASc scores > 2 were identified as an effective predictive cut-off point for all-cause mortality in STEMI (area under curve = 0.850, 95% confidence interval: 0.819-0.878, P < 0.001). CHA2DS2-VASc score > 2 yielded a sensitivity of 70.18% and a specificity of 83%.
Conclusion: The CHA2DS2-VASc is a simple and easily calculated score that provides an additional level of risk stratification beyond that provided by conventional risk scores in predicting in-hospital and long-term all-cause and cardiovascular mortality in STEMI.