Ferritin and body mass index predict cardiac dysfunction in female adolescents with anorexia of the restrictive type

M.K.F. Docx; J. Weyler; A. Simons; J. Ramet; G. Veereman; L. Mertens

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Title: Ferritin and body mass index predict cardiac dysfunction in female adolescents with anorexia of the restrictive type
Author(s): M.K.F. Docx , J. Weyler , A. Simons , J. Ramet , G. Veereman , L. Mertens
Journal: Acta Cardiologica
Volume: 70 Issue: 4 Date: 2015
Pages: 395-399
DOI: 10.2143/AC.70.4.3094647

Abstract :
Background and aim: Decreased left ventricular mass index in anorexia nervosa is amply reported. The aim of this study is to identify non-burdensome predictors of reduced left ventricular mass/height^2.7 (cLVM) in a cohort of adolescent restrictive anorexic girls.
Methods: This is a retrospective study of all anorexic girls of the restrictive type referred to our tertiary eating disorder unit between September 2002 and December 2012, for somatic assessment of weight loss. All subjects fulfilled DMS-IV criteria, without a family history of cardiac or cardiovascular diseases.
Results: In all, 283 restrictive anorexic girls (age: 14.63 ± 1.65 y; body mass index: 15.72 ± 1.81 kg/m²) were included. Ferritin and body mass index were independent, statistically significant predictors of the corrected left ventricular mass (P < 0.05).
Conclusion: Decreased cLVM is very common in anorexia nervosa of the restrictive type. Two factors predicted decreased cLVM in our population: ferritin and BMI.