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Document Details : Title: Prognostic value of elevated mean platelet volume in patients undergoing primary angioplasty for ST-elevation myocardial infarction Author(s): O. Akgul , H. Uyarel , H. Pusuroglu , M. Gul , N. Isiksacan , S. Turen , M. Erturk , O. Surgit , M. Cetin , U. Bulut , O.F. Baycan , N. Uslu Journal: Acta Cardiologica Volume: 68 Issue: 3 Date: 2013 Pages: 307-314 DOI: 10.2143/AC.68.3.2983426 Abstract : Objective: The aim of this study was to evaluate the prognostic value of mean platelet volume (MPV) in patients with STEMI undergoing primary percutaneous coronary intervention (PCI). Methods: We prospectively enrolled 495 consecutive STEMI patients. The study population was divided into tertiles based on admission MPV values. The high MPV group (n = 148) was defined as a value in the third tertile (> 8.9), and the low MPV group (n = 347) included those patients with a value in the lower two tertiles (≤ 8.9). Clinical characteristics, in-hospital and six-month outcomes of primary PCI were analysed. Results: Higher six-month all-cause mortality rates were observed in the high MPV group In Cox multivariate analysis; a high admission MPV value (> 8.9) was found to be a powerful independent predictor of six-month all-cause mortality. Conclusions: These results suggest that a high admission MPV level was associated with increased six-month all-cause mortality in patients with STEMI undergoing primary PCI. |
