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Document Details : Title: T-wave alternans and beat-to-beat variability of repolarization: pathophysiological backgrounds and clinical relevance Author(s): V. Floré , R. Willems Journal: Acta Cardiologica Volume: 67 Issue: 6 Date: 2012 Pages: 713-718 DOI: 10.2143/AC.67.6.2184675 Abstract : In this review, we focus on temporal variability of cardiac repolarization. This phenomenon has been related to a higher risk for ventricular arrhythmia and is therefore interesting as a marker of sudden cardiac death risk. We review two non-invasive clinical techniques quantifying repolarization variability: T-wave alternans (TWA) and beat-to-beat variability of repolarization (BVR). We discuss their pathophysiological link with ventricular arrhythmia and the current clinical relevance of these techniques. |
