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Document Details :

Title: Ultraviolet light-enhanced visualization of cutaneous signs of carotene and vitamin A dietary deficiency
Author(s): UHODA E, PETIT L, PIÉRARD-FRANCHIMONT C, PIÉRARD GE
Journal: Acta Clinica Belgica
Volume: 59    Issue: 2   Date: 2004   
Pages: 97-101
DOI: 10.2143/ACB.59.2.2050391

Abstract :






may induce specific changes in the skin biology and structure. Vitamin A defi ciency is well identified as a cause of xerosis and follicular keratosis. Skin of the forehead and balding scalp was examined in 3 homeless alcoholic men who suffered from altered liver functions and denutrition including carotene and vitamin A deficiencies. The ultraviolet light-enhanced visualization (ULEV) method was used with a computer-assisted video camera equipped with an internal ultravioletemitting unit. Twenty healthy age-and phototype-matched men served as controls. Subclinical alterations of the stratum corneum and tiny follicular horny spikes at the skin surface were disclosed by ULEV. They were consistent with discrete flakiness on the forearms. By contrast, skin of the face and scalp showed follicular horny impactions corresponding to kerosis without any evidence for interfollicular xerosis. The skin condition was markedly improved after a 10-week dietary normalization. It is concluded that the ULEV method reveals some of the mildest and subclinical skin changes secondary to carotene and vitamin A deficiency. It could tentatively be used as a cheap and non-invasive aid in clinical screening programs among populations at risk.