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Document Details : Title: Heart failure with mitral valve regurgitation due to primary hyperoxaluria type 1 Subtitle: Case report with review of the literature Author(s): VAN DRIESSCHE, L. , DHONDT, A. , DE SUTTER, J. Journal: Acta Cardiologica Volume: 62 Issue: 2 Date: 2007 Pages: 202-206 DOI: 10.2143/AC.62.2.2020243 Abstract : Primary hyperoxaluria type 1 (PH1) is a rare recessive autosomal disorder characterized by systemic calcium oxalate depositions, that results in renal failure and systemic oxalosis. We report a 38-yearold male with cardiac oxalosis, a severe complication of PH1, presenting with an infiltrative cardiomyopathy, secondary heart failure and severe mitral regurgitation, necessitating surgical repair to allow combined liver-kidney transplantation. We discuss pathogenesis, diagnostics and therapy of this clinical entity by reviewing literature. |
