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Document Details :
Title: Celiprolol-induced lupus-like syndrome
Author(s): CHARNIOT, Jean-Christophe , GENEREAU, Thierry , MOUTHON, Luc
Journal: Acta Cardiologica
Volume: 61 Issue: 6 Date: December 2006
Systemic lupus erythematosus can be idiopathic or drug-induced. Although a number of beta-blockers have been reported to induce a lupus-like syndrome, to the best of our knowledge, no such case has been described following celiprolol therapy.We diagnosed a lupus-like syndrome in a 67-year-old female patient who developed febrile polyarthritis,percarditis,antinuclear and anti-histone antibodies after taking celiprolol for 2 years. Despite drug withdrawal, prolonged corticotherapy was needed to obtain clinical and biological remission.