Heart rate variability in neurally mediated reflex syncope

ARSLAN, Uġur; ÖZDEMIR, Murat; TÜRKOǦLU, Sedat; YAZICI, Güliz Erdem; ÇENGEL, Atiye

Document Details :

Title: Heart rate variability in neurally mediated reflex syncope
Author(s): ARSLAN, Uġur , ÖZDEMIR, Murat , TÜRKOǦLU, Sedat , YAZICI, Güliz Erdem , ÇENGEL, Atiye
Journal: Acta Cardiologica
Volume: 61 Issue: 6 Date: December 2006
Pages: 599-602
DOI: 10.2143/AC.61.6.2017957

Abstract :
Objective— The aim of this study was to investigate the heart rate variability (HRV) parameters
in patients with neurally mediated reflex syncope.
Methods — Thirty-three patients (10 men,age range 16-50 years) who were scheduled to undergo head-upright tilt test (HUTT) with a typical history of vasovagal syncope (VVS) underwent 24-hour Holter monitoring in an attempt to study HRV parameters. Sixteen individuals without syncope and similar baseline characteristics made up the control group.

Results — Seventeen of the 33∞∞syncopal patients showed HUTT positivity.All the time domain HRV parameters except the mean RR interval were higher in the HUTT (+) syncopal patients than in the negative responders. Although not statistically significant, the positive responders had higher NN50, pNN50, RMSSD and SDNNi values than the control group.HUTT (-) VVS patients had lower SDNN and SDANN values when compared with the control group.The other HRV parameters did not differ significantly between the HUTT (-) patients and the control group.

Conclusion — Increased parasympathetic tonus as reflected by significantly higher HRV parameters is associated with a greater frequency of HUTT positivity in patients with syncope and no organic heart disease.

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