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Document Details :

Title: Late-term results of mitral valve replacement with St. Jude® mechanical valve prosthesis
Subtitle: Samsun experience
Author(s): DEMIRAG, Mustafa Kemal , KECELIGIL, Hasan Tahsin , KOLBAKIR, Fersat
Journal: Acta Cardiologica
Volume: 61    Issue: 5   Date: October 2006   
Pages: 537-544
DOI: 10.2143/AC.61.5.2017769

Abstract :
Background and aim of the study — We have reported the short- and long-term results of mitral valve replacement in this article.

Methods — Mitral valve replacement was conducted in 276∞∞patients in our clinic between January 1989 and March 2005. The youngest patient was 4 years old and the oldest patient was 74 years old. Mean age was 40.08 ± 1.06 y. Of these patients, 41.3% were men and 58.7% were women. The reason for operation was mitral stenosis in 96 patients (34.78%), mitral insufficiency in 78 patients (29.26%) and mitral stenosis plus mitral insufficiency in 102 patients (36.96%). The aetiology of mitral valve lesions was acute rheumatic fever in 208 patients (75.36%). The aetiology of mitral valve lesions was degenerative in 37 patients (13.41%), ischaemic in 23 patients (8.33%) and congenital in 8 patients (2.9%).

Results — In the 5, 10 and 15-year periods, the actual survival rates were 87.64% ± 2.02%, 83.35% ± 2.38% and 68.19% ± 5.63%, respectively.Thromboembolism was observed in 38 patients (13.77%). The rates of actual freedom from thromboembolism in the 5, 10 and 15-year periods were 93.08% ± 1.53%,88.48% ± 1.99% and 81.06% ± 3.43%, respectively. Of the 276 patients who had been observed for 15 years, 5 had (1.81%) valvular thrombosis. The rates of actual freedom from valvular thrombosis in the 5, 10 and 15-year periods were 98.89% ± 0.64%, 98.04% ± 0.87% and 98.04% ± 0.87%, respectively. In the 15-year period, 23 patients (8.33%) had haemorrhage due to anti-coagulation. The rates of actual freedom from haemorrhage due to anti-coagulation in the 5,10 and 15-year periods were 95.64% ± 1.23%, 93.40% ± 1.56% and 87.73% ± 2.96%, respectively. Seven patients (2.54%) had prosthetic valvular endocarditis.The rates of actual freedom from endocarditis in the 5, 10 and 15-year periods were 98.51% ± 0.74%, 97.60% ± 0.97% and 97.01% ± 1.13%, respectively. Nine patients (3.27%) were re-operated. The rates of actual freedom from re-operation in the 5, 10 and 15-year periods were 97.45% ± 0.95%, 96.58% ± 1.12% and 96.58% ± 1.12%, respectively.

Conclusions — St. Jude Medical® mechanical valve prosthesis has been the valve of choice in our clinic owing to its excellent haemodynamic properties and low rates of complication.