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Document Details : Title: Duchenne's Cardiomyopathy Subtitle: Two Case Reports Author(s): GUO, Hangyuan , SHEN, Jianyao , LEE, Jong-Dae Journal: Acta Cardiologica Volume: 61 Issue: 4 Date: August 2006 Pages: 475-480 DOI: 10.2143/AC.61.4.2017311 Abstract : We describe two cases of Duchenne’s cardiomyopathy with severe cardiac dysfunction, sporadic episodes of myoglobinuria induced by effort and increased levels of serum creatine kinase. Very mild signs of skeletal myopathy were clinically evident. Left ventriculography showed diffuse severe hypokinesia. Skeletal muscle biopsy demonstrated a dystrophic process. The patients had no familial background of the disease. These 2 patients might have a sporadic inheritance pattern with severe cardiac involvement. |