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Document Details :

Title: Duchenne's Cardiomyopathy
Subtitle: Two Case Reports
Author(s): GUO, Hangyuan , SHEN, Jianyao , LEE, Jong-Dae
Journal: Acta Cardiologica
Volume: 61    Issue: 4   Date: August 2006   
Pages: 475-480
DOI: 10.2143/AC.61.4.2017311

Abstract :
We describe two cases of Duchenne’s cardiomyopathy with severe cardiac dysfunction, sporadic episodes of myoglobinuria induced by effort and increased levels of serum creatine kinase. Very mild signs of skeletal myopathy were clinically evident. Left ventriculography showed diffuse severe hypokinesia. Skeletal muscle biopsy demonstrated a dystrophic process. The patients had no familial background of the disease. These 2 patients might have a sporadic inheritance pattern with severe cardiac involvement.