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Document Details :

Title: Effects of thrombolysis in the evolution of right bundle-branch block complicating an acute anterior myocardial infarction
Author(s): ALEGRET, Josep M. , MARTÍ, Vicens , RODRÍGUEZ-FONT, Enrique , ALONSO, Concepción , GUINDO, Josep , DOMÍNGUEZ DE ROZAS, Jose M.
Journal: Acta Cardiologica
Volume: 56    Issue: 5   Date: October 2001   
Pages: 297-301
DOI: 10.2143/AC.56.5.2005690

Abstract :
Introduction — There is scant information about the effects of thrombolysis in the evolution of right bundle-branch block (RBBB) in the setting of acute anterior myocardial infarction. The aim of this study has been to analyse these effects and its impact on prognosis.

Methods — We studied 54 patients who presented a RBBB related to an acute anterior myocardial infarction. We defined two groups: those who received thrombolytic treatment and those who did not. We analysed the evolution of RBBB (transience, moment of onset, moment of disappearance) and its relationship with in-hospital mortality.Twenty-one patients (39%) received thrombolytic treatment (group T) and 33 patients (61%) (group NT) did not.

Results — The incidence of late appearance (> 6 h) of RBBB was less frequent in group T compared with group NT (10% vs. 33%, p = 0.04).The incidence of transient block was similar in the two groups (57% vs. 45%, p ns). However, early disappearance of RBBB (in < 6 hours) was more common in group T than in group NT (33% vs. 9%, p = 0.04). Mortality was higher in patients with RBBB present at 24 h after admission) than in those with RBBB resolved in less than 24 hours (in group NT, 55% vs. 8%, p = 0.02 and in group T 50% vs. 0%, p = 0.02, respectively).

Conclusions — Thrombolysis seems to influence the moment of onset and disappearance of RBBB by promoting its early disappearance and avoiding its late appearance.Disappearance of RBBB is associated with a better prognosis.