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Document Details :

Title: Blood pressure and urinary cations in a low-fat intake Chinese population sample
Author(s): XIE, Jinxiang , LIU, Lisheng , KESTELOOT, Hugo
Journal: Acta Cardiologica
Volume: 56    Issue: 3   Date: June 2001   
Pages: 163-168
DOI: 10.2143/AC.56.3.2005636

Abstract :
Background — The relationship between cation intake and blood pressure (BP) in populations with specific dietary habits such as a low fat intake, remains unclear. A low fat intake has been prevalent during human evolution.

Methods — The average of 6 BP readings and heart rate (HR) recordings has been calculated. Dietary intake was measured using the 24h recall-method. A 24h urine sample was collected.

Results — A highly significant correlation was found between the sodium/potassium ratio (Na/K), after adjustment for age, weight, height, heart rate, alcohol intake and sex and systolic blood pres- sure (SBP), diastolic blood pressure (DBP) and pulse pressure (PP). The same applies to the sodium/creatinine (Na/Cr) and potassium/creatinine (K/Cr) ratios, with a positive correlation for Na/Cr and a negative one for K/Cr.The partial regression coefficient was in absolute value about 4-5 times greater for K/Cr than for Na/Cr. Age correlates highly significantly and independently with both SBP and DBP.

Conclusion — If a Na/K ratio of 1 is considered optimal, by achieving that goal mean SBP could be reduced by about 6 mm Hg and mean DBP by 3 mm Hg in this normotensive population.