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Document Details : Title: Effect of haemodialysis on left atrial mechanical function in patients with chronic renal failure Author(s): YILMAZ, Mustafa , EROL, Mustafa Kemal , CETINKAYA, Ramazan , ALP, Necip Journal: Acta Cardiologica Volume: 57    Issue: 4   Date: August 2002    Pages: 257-260 DOI: 10.2143/AC.57.4.2005422 Abstract : Objective— The aim of this study was to investigate the potential effects of haemodialysis on left atrial (LA) mechanical functions in patients with chronic renal failure. Methods— Thirty-two patients with chronic renal failure (mean age 42.8 ±19.6 years) were included in this study.LA volumes were determined echocardiographically at the time of mitral valve opening (maximal, Vmax),at the onset of atrial systole (p wave at the electrocardiography = Vp) and at the mitral valve closure (minimal, Vmin) according to the biplane area-length method in apical 4-chamber and 2-chamber view. All volumes were corrected to the body surface area, and the following left atrial emptying functions were calculated. LA passive emptying volume = Vmax – Vp,LA passive emptying fraction = LA passive emptying volume/ Vmax.Conduit volume = LV stroke volume-(Vmax – Vmin), LA active emptying volume = Vp – Vmin. LA active emptying fraction = LA active emptying volume / Vp, LA total emptying volume = (Vmax – Vmin), LA total emptying fraction = LA total emptying volume / Vmax. Results— Mean fluid removal was 1875±812 milliliter.There was no difference between in the LA passive emptying volume before and after dialysis (10.83±7.44 vs.11.47±7.73 cm3/m2,p > 0.05). Conduit volume (from 15.30±10.68 to 10.31±6.83 cm3/m2, p < 0.05),LA active emptying volume (from 12.61±6.39 to 9.25±4.40 cm3/m2, p < 0.005), LA total emptying volume (from 23.44±8.52 to 20.72 ±8.58 cm3/m2,p < 0.05), LA maximal volume (from 39.44±14.07 to 28.89±11.80 cm3/m2, p < 0.001), LA minimal volume (from 15.99±9.70 to 8.17±4.52 cm3/m2,p < 0.001), and the volume at the onset of atrial systole (from 28.61±10.36 to 17.42±7.20 cm3/m2, p < 0.001) decreased significantly after the haemodialysis session,whereas LA passive emptying fraction (from 0.27±0.14 to 0.38±0.14%, p < 0.001), LA active emptying fraction (from 0.46±0.18 to 0.53±0.17%, p < 0.05), LA total emptying fraction (from 0.61±0.14 to 0.72±0.09%,p < 0.001) increased significantly after haemodialysis. Conclusion— The results of this study suggest that left atrial mechanical functions improve after haemodialysis in patients with chronic renal failure.