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Document Details :

Title: A case of HELLP syndrome: an immuno-“logical” approach
Author(s): HEGGERMONT WA, VERHELST C, DE WILDE K, DE PAEPE M, LACQUET F, VONCK A
Journal: Acta Clinica Belgica
Volume: 67    Issue: 5   Date: 2012   
Pages: 375-377
DOI: 10.2143/ACB.67.5.1003135

Abstract :






We report on a 27-year-old woman who developed severe arterial hypertension on a background of general malaise within 48 hours after vaginal delivery, suggesting severe acute-onset pre-eclampsia. Concomitant biochemical observations of haemolysis, elevated liver tests and low platelets lead to the diagnosis of (post-partum) HELLP syndrome. Our patient was transferred immediately to the intensive care unit (ICU), where she underwent plasmapheresis in combination with intravenous glucocorticoids, nicardipine and labetalol. Our patient recovered fully after three plasmapheresis sessions. Genetic testing of mutations responsible for complement deficits was negative.