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Document Details : Title: Probable hypersensitivity reaction to vancomycin associating rash, fever and neutropenia Author(s): DAUBY N, FINK W, SEYLER L, LUCE S, NOUWYNCK C, TAS S, JACOBS F Journal: Acta Clinica Belgica Volume: 67 Issue: 3 Date: 2012 Pages: 226-228 DOI: 10.2143/ACB.67.3.1003068 Abstract : We describe the case of a 54-year old woman with breast cancer who was treated by vancomycin for febrile neutropenia due to a methicillin-resistant Staphyloccocus epidermidis infection of a surgically implanted catheter. She developed an hypersensitivity reaction to vancomycin associating neutropenia, fever, skin rash and elevated liver enzymes following re-challenge with vancomycin after having been misdiagnosed with septic thrombophlebitis. Following this re-challenge, neutrophils count fell dramatically but promptly resolved after cessation of vancomycin. |
