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Document Details :

Title: Fatal overdose with trazodone: case report and literature review
Author(s): DE MEESTER A, CARBUTTI G, GABRIEL L, JACQUES JM
Journal: Acta Clinica Belgica
Volume: 56    Issue: 4   Date: 2001   
Pages: 258-261
DOI: 10.2143/ACB.56.4.1002857

Abstract :






A fatal case of suicide with trazodone alone in a 40-year-old patient is reported. Life-threatening arrhythmias, such as torsades de pointes and complete AV block, are recorded. Blood collected at admission contained a trazodone toxic concentration of 25.4 μg/mL. The patient developed multiple organ failure and died less than 24 hours after his admission to the emergency department. The authors discuss the effects of overdose of trazodone, a well-known safe antidepressant drug.