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Document Details : Title: New insights into insulin resistance pathophysiology: how it affects glucose and lipid metabolism Author(s): COL V Journal: Acta Clinica Belgica Volume: 56 Issue: 3 Date: 2001 Pages: 155-162 DOI: 10.2143/ACB.56.3.1002845 Abstract : Insulin resistance is a metabolic state encountered in many physiological and physiopathological conditions. Its pivotal effect on glucose and lipid metabolism is increasingly recognised. Over the last few years, numerous molecular/intracellular pathways affected by this condition have been elucidated. The author reviews some recent findings underlying several major metabolic abnormalities. An overview of current and future therapeutics is also provided. |
