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Document Details : Title: Management of hypertension Author(s): DE LEEUW PW, KROON AA Journal: Acta Clinica Belgica Volume: 58 Issue: 5 Date: 2003 Pages: 308-313 DOI: 10.2143/ACB.58.5.1002762 Abstract : Presently, many drugs are available for the treatment of patients with high blood pressure. Although there are several theoretical arguments favouring one particular type of drug over the other, prospective clinical trials have failed to show major differences between drug classes in terms of overall prognosis. A possible exception in this regard may be the development of diabetes mellitus which seems to occur less frequently with ACE inhibitors, AT1 receptor blockers and calcium entry blockers than with diuretics. The choice of the antihypertensive drug regimen should take certain patient characteristics into account, notably comordid conditions. However, despite theoretical considerations concerning initial therapy many patients will end up using two or more medications. |
