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Document Details : Title: Haemolytic anaemia caused by piperacillin-tazobactam Author(s): DAPPER I, NAUWYNCK M, SELLESLAG D, HIDAJAT M, BOURGEOIS M, MARTENS P, WILMER A Journal: Acta Clinica Belgica Volume: 64 Issue: 6 Date: 2009 Pages: 517-519 DOI: 10.2143/ACB.64.6.1002530 Abstract : We report a case of haemolytic anaemia due to the use of piperacillin-tazobactam in a 50-year old woman. Since 2002 4 other cases were reported. Either the presence of piperacillin as tazobactam can induce haemolysis. In all cases discontinuating the drugs resolves the haemolysis. Although drug-induced haemolytic anaemia due to piperacillin-tazobactam is rare, the common use of this antibioticum in the critical care setting should alert the physician as a possible culprit in cases of haemolytic anaemia. |