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Document Details : Title: Low-molecular-weight heparin-induced skin necrosis: about 2 cases Author(s): YOMBI JC, BELKHIR L, DE BAERE T, DUBUC JE, HAINAT P Journal: Acta Clinica Belgica Volume: 64 Issue: 3 Date: 2009 Pages: 228-230 DOI: 10.2143/ACB.64.3.1002490 Abstract : Heparin-induced skin necrosis is an infrequent condition, complicating unfractionated heparin and more rarely low-molecular-weight heparin administration. Like heparin-induced thrombocytopenia, it is associated with the presence of anti-PF4 antibodies. After reporting 2 observations, we briefl y review the clinical features and management of this condition. Early recognition is of the utmost importance since heparin-induced skin necrosis can be associated with HIT, a potentially lethal disorder. |
