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Document Details :

Title: Panhypopituitarism apparently caused by hypophysitis masking a rapid development of a craniopharyngioma. A case report.
Author(s): JOOSEN P, ABRAMS P, VERHELST J, PARIZEL PM, SALGADO R, ABS R
Journal: Acta Clinica Belgica
Volume: 65    Issue: 2   Date: 2010   
Pages: 133-135
DOI: 10.2143/ACB.65.2.1002399

Abstract :






We report the case of a 39-year old male presenting with panhypopituitarism and diabetes insipidus. MR imaging showed focal thickening of the pituitary infundibulum and infiltration of the anterior pituitary lobe, suggesting hypophysitis. Hormonal replacement therapy induced a pronounced amelioration of general well-being. Eight months later the subject developed visual disturbances. MR imaging now showed a cystic sellar mass. Surgical drainage was performed. A second operation was necessary six weeks later because of recurrent visual field defects. Diagnosis of papillary craniopharyngioma was finally made. This case demonstrates the remarkably rapid development of a craniopharyngioma, of which the initial radiological appearance was suggestive of hypophysitis. It also emphasizes the need of repeat MR examination in case of unusual presentation of hypopituitarism.