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Document Details : Title: Medical and surgical management of paraneoplastic pyoderma gangrenosum - a case report and review of the literature Author(s): LAMET S, BRACKE A, GELUYKENS E, VLIEGHE E, SEYMONS K, GADISSEUR AP, VRELUST I, VAN MARCK V, SOMVILLE J, LAMBERT J Journal: Acta Clinica Belgica Volume: 65 Issue: 1 Date: 2010 Pages: 37-40 DOI: 10.2143/ACB.65.1.1002382 Abstract : We present a case of a 44 year old male with pyoderma gangrenosum (PG) presenting simultaneously with diagnosis of acute leukemia. His skin disease was stabilized with corticosteroids and most lesions cleared after chemotherapy-induced remission of the malignancy, but the largest lesion remained necrotic. Surgical treatment of the large necrotic ulcer included debridement followed by split-thickness skin graft while maintaining corticoid therapy. Unfortunately, relapse of the pyoderma gangrenosum with bullous lesions heralded relapse of the ultimately fatal malignancy. This case illustrates: 1. PG presenting simultaneously with a haematologic malignancy 2. Relapse with atypical bullous lesions with return of the malignancy and 3. The use of surgical modalities in managing patients with PG, a disease notorious for surgical complications. |
