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Document Details :

Title: Percutaneous transcatheter closure if atrial septal defects: Initial single-centre experience and follow-up results
Subtitle: Initial experience with three-dimensional echocardiography
Author(s): DE RIDDER, Serge , SUTTORP, Maarten-Jan , ERNST, Sjef M.P.G. , SIX, Jacob A. , MANNAERTS, Herman F.J. , KAMP, Otto , PLOKKER, Thijs H.W.M. , JAARSMA, Wybren
Journal: Acta Cardiologica
Volume: 60    Issue: 2   Date: April 2005   
Pages: 171-178
DOI: 10.2143/AC.60.2.2005028

Abstract :
Objective — Registry to report our single-centre experience in closing defects of the atrial septum.

Methods — Between 1996 and 2001, transcatheter device closure of significant atrial septal defects was performed in 32 adults (mean age 45.1 years, range from 15 to 76 years), using different device types. Six patients had a patent foramen ovale (PFO) and 26 patients had a secundum atrial septal defect (ASD II). Defects were selected by means of two-dimensional transoesophageal echocardiography (2D TOE). For 12 defects additional three-dimensional transoesophageal echocardiography (3D TOE) was performed.

Results — Mean balloon-stretched diameter was 19.3 mm (range from 11 to 24 mm). A device was successfully placed in all PFO patients (100%) without complications at follow-up. Successful immediate device placement occurred in 24 out of 26 ASD patients. Two immediate placement failures, 1 device embolisation and 1 device non-fixation, occurred and required urgent surgery. There was 1 patient with pericardial effusion after the intervention, requiring pericardiocentesis. Three late placement failures occurred: 2 device embolisations and 1 device dislocation. Clinical success after 3 to 6 months follow-up, defined as the absence of shunt or small shunt, was achieved in all 6 PFO patients and in 21 out of 23 ASD patients (1 device embolisation, requiring surgery, occurred before follow-up was completed). Two patients with significant shunt, 1 late device dislocation and 1 late device embolisation, underwent elective surgery. For patient selection, 3D TOE proved useful in the evaluation of large and/or complex defects.

Conclusion — Transcatheter device closure of carefully selected atrial septal defects is an alternative to surgery. Although the results are promising, surgical back-up is often needed.