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Document Details : Title: Status of intracellular and extracellular magnesium concentration in patients with cardiac syndrome X Author(s): GUO, Hangyuan , LEE, Jong-Dae , GUO, Ming , LU, Yong , TANG, Fengqin , UEDA, Takanori Journal: Acta Cardiologica Volume: 60 Issue: 3 Date: June 2005 Pages: 259-263 DOI: 10.2143/AC.60.3.2005001 Abstract : Objectives — This study sought to clarify the differences of intracellular and extracellular magnesium levels in patients with cardiac syndrome X. Methods — We evaluated the intracellular and extracellular magnesium status of 22 patients with cardiac syndrome X (group A) and 22 age – and gender – matched disorder-free control subjects (group B). Levels of magnesium were determined in serum, urine, erythrocytes, and the 24-h magnesium retention rate was calculated by a magnesium loading test. Results — Group A showed a higher 24-h magnesium retention rate (49.8 ± 11.3% vs. 32.6 ± 7.5%, p < 0.05) and a lower intracellular concentration of magnesium in erythrocytes than group B (3.7 ± 1.4 vs. 5.6 ± 1.3 fg/cell, p < 0.05), demonstrating the presence of magnesium deficiency in group A. There were no significant differences in the serum concentration of magnesium between groups A and B (0.87 ± 0.23 vs. 0.83 ± 0.15 mmol/l). Conclusions — This study demonstrated that the intracellular magnesium level decreased in patients with cardiac syndrome X. |
