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Document Details : Title: Coronary artery calcification and dietary cholesterol intake in Korean men Author(s): OH, Kyung Won , NAM, Chung Mo , JEE, Sun Ha , CHOE, Kyu Ok , SUH, Il Journal: Acta Cardiologica Volume: 57 Issue: 1 Date: February 2002 Pages: 5-11 DOI: 10.2143/AC.57.1.2005372 Abstract : Objective — This study was performed to examine the relationship between dietary cholesterol intake and coronary artery calcification (CAC) score in healthy men. Methods — Electron beam computed tomography (EBCT) was used to examine the CAC score in 135 Korean men aged 40-81 years who did not have clinical illness. Dietary cholesterol intake was assessed by a nutritionist using a semiquantitative food frequency method. Body mass index (BMI), serum lipid levels, cigarette use, alcohol intake, exercise, and a past history of cardiovascular disease were determined during interview and examination. Results — The resultant median CAC score among those who experienced CAC was 22.5 (1-697) and average intakes of total fat and cholesterol were 22.4% (13.8-40.7) of total energy intake and 306.0 mg/day (84-1191). When the participants were classified into high (≥75 percentile) and low (< 75 percentile) CAC score groups, multiple logistic analysis showed that the cholesterol intake (per 10 mg/1000 kcal of energy) was significantly related to a high CAC score (OR 1.12: 95% CI 1.02 – 1.24), after adjustment for age, BMI, serum triglyceride level, past history of hypertension, past history of hyperlipidaemia, and energy intake. Also, when participants were classified into 2 groups (CAC score ≥100 vs.< 100),cholesterol intake was found to be significantly related to CAC score. However, fatty acid intakes were not significantly related to the CAC score. Conclusion — These results suggest that in a population with a relatively low risk of coronary heart disease, higher cholesterol intake may increase the level of CAC. |
