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Document Details : Title: Disorders of glucose metabolism in human immunodeficiency virus-infected patients Author(s): BENHALIMA K, MATHIEU C, VAN WIJNGAERDEN E Journal: Acta Clinica Belgica Volume: 63 Issue: 4 Date: 2008 Pages: 227-234 DOI: 10.2143/ACB.63.4.1002569 Abstract : Over the past 10 years, the development of highly active antiretroviral therapy (HAART) has dramatically improved morbidity and mortality in human immunodeficiency virus (HIV)-infected patients. Since the introduction of HAART however, unexpected metabolic abnormalities, including lipodystrophy, dyslipidaemia and dysregulation of glucose metabolism, are reported with increasing frequency in HIV-infected persons. Such metabolic disorders, if not treated, may be associated with an increased risk of cardiovascular disease in HIV infected patients. In this paper, the prevalence, mechanisms and therapeutic strategies for the disorders of glucose metabolism in the context of HIV-infection are discussed. |
